The Rf Value of Paracetamol in Ethyl Acetate (Rf Value of Paracetamol in Ethyl Acetate) must be strictly examined. Prepare all kinds of equipment, a clean chromatography cylinder, a thin layer plate of suitable size, and a uniform silicone coating on its surface, such as the flat of a mirror, to prepare for the signs of the experiment. Take an appropriate amount of acetaminophen and dissolve it with a suitable solvent to form a clear liquid, such as the clarity of a clear spring. Then take ethyl acetate, which is pure and stable in quality, and is the important agent for the experiment.

Order of operation
Lightly immerse the thin-layer plate in the liquid containing acetaminophen, and it will come out in a moment. The liquid is evenly dipped on the surface, like exposed leaves. Wait for it to air dry naturally, and then place it in a chromatography cylinder containing ethyl acetate. The cylinder head is tightly closed to prevent it from venting. Looking at it, the liquid is slowly climbing on the plate, like the flow of a stream. The components of acetaminophen move with the liquid, each showing its own behavior.

Analysis of results
When the liquid stops rising, take out the thin-layer plate and develop color by a specific method. Looking at it, the traces left by acetaminophen are clearly discernible. Measure the migration distance and compare it with the liquid rising distance to get the specific shift value. Repeat the experiment to observe the change of the value. If the value is stable but rarely changed, the reliability of the experiment will be proved; if the value fluctuates irregularly, the error of the operation and the difference of the drug will be considered. After studying, a stable and comparable Rf value in acetaminophen and ethyl acetate can be obtained, which is a lesson for future events.