Dosage of Prednisolone Acetate to Dogs

There are many canine diseases. During the treatment process, the rational use of prednisolone acetate as a common drug is crucial, and the accurate control of the dosage is the key.

Initial Dosage for Different Conditions
For some inflammatory diseases, such as mild arthritis, the recommended initial dose is generally 0.5-1 mg prednisolone acetate per kilogram of body weight. If the dog has a more serious autoimmune disease, such as systemic lupus erythematosus, the initial dose may need to be increased to 1-2 mg per kilogram of body weight. This is because autoimmune diseases are often complex and severe, requiring adequate doses of drugs to control an overactive immune system.

Frequency of Dosing
Usually, daily dosing is required in the initial stage to ensure that the drug can maintain an effective blood concentration in the dog, so as to play a better role. As the disease gradually stabilizes, the dosing frequency can be adjusted appropriately according to the veterinarian's evaluation, such as changing to alternate day dosing. This can not only continue to control the disease, but also reduce the adverse reactions caused by long-term use of the drug to a certain extent.

Dose Adjustment Principles
During the treatment process, close attention should be paid to the changes in the dog's condition. If the symptoms improve significantly, the dose can be gradually reduced under the guidance of the veterinarian. However, the reduction should not be too large, each reduction is about 10% - 20% of the original dose, and observe the dog's reaction after the reduction. If the disease repeats, it is necessary to return to the original dose or increase the dose appropriately. For example, when the dog's skin inflammation is significantly reduced after a period of medication, erythema is reduced, and itching is relieved, the dose reduction can be considered at this time. However, if the dog starts to scratch frequently and the skin symptoms worsen again after the reduction, the dose should be adjusted in time.

Precautions
When using prednisolone acetate, it is necessary to follow the veterinarian's advice and do not increase or decrease the dose at will. Because improper dosage may not only affect the treatment effect, but also cause many adverse reactions. For example, long-term high-dose use may lead to Cushing's syndrome-like symptoms in dogs, such as drinking more, eating more, polyuria, abdominal enlargement, and thinning of the skin. At the same time, during the medication period, the dog should be regularly taken for physical examination, monitoring blood routine, liver and kidney function and other indicators, so as to detect potential problems in time and take corresponding measures.