Potassium Acetate Buffer Formula
Now to make potassium acetate buffer, the method is as follows.

The first things required are acetic acid (CH < COOH) and potassium acetate (CH < COOK). Measure an appropriate amount of acetic acid, because it is acidic; and then weigh an appropriate amount of potassium acetate, because it is alkaline. The combination of the two can be used as a buffer.

If you want to make a buffer with a pH of a certain value, you need to follow the Henderson-Hasselbalch formula: pH = pKa + log ([A]/[HA]). Among them, the pKa value of acetic acid is about 4.76, [A] is the concentration of acetate ions (that is, those ionized by potassium acetate), and [HA] is the concentration of acetic acid.

If you want to make a buffer solution with pH = 5, you can substitute the formula to get 5 = 4.76 + log ([CH-COO]/[CH-COOH]). After calculation, the ratio of [CH-COO]/[CH-COOH] can be determined. According to this ratio, the amount of acetic acid and potassium acetate can be determined.

Weigh a certain amount of potassium acetate and dissolve it with an appropriate amount of distilled water to obtain a potassium acetate solution. Then measure an appropriate amount of acetic acid and slowly add it to the above solution. While adding, measure its pH with pH until the desired pH is reached.

Finally, transfer the resulting buffer to a clean container, label it with ingredients, pH value, and preparation date, etc., and store it properly for later use.