Fluorometholone vs Prednisolone Acetate
Comparison of Fluorometholone and Prednisolone Acetate
In the medical field, the effect of drugs is related to the recovery of the disease. Now on Fluorometholone and Prednisolone Acetate, the two have similarities and differences in pharmacological effects, applicable diseases, side effects and usage, etc. Doctors need to be carefully examined.

Pharmacological Properties
Fluorometholone is a glucocorticoid drug, which can bind to intracellular glucocorticoid receptors, through a series of intracellular signal transduction, regulate gene transcription, inhibit the production and release of inflammation-related factors, such as inhibiting interleukin, tumor necrosis factor, etc., so as to achieve anti-inflammatory effects. Its anti-inflammatory power is relatively mild, and the effect on intraocular pressure is relatively slight.

Prednisolone acetate is also a glucocorticoid. It is metabolized into active prednisolone by the liver. After binding to the receptor, it regulates gene expression, inhibits the activity of phospholipase A 2O, and reduces the synthesis of inflammatory mediators such as prostaglandins and leukotrienes. The anti-inflammatory effect is significant, but it has a slightly greater impact on intraocular pressure.

Applicable diseases
Flumerelone is commonly used for eye inflammation, such as blepharitis, conjunctivitis, keratitis, etc. It is especially suitable for high hormone sensitivity and needs to control inflammation, while avoiding excessive increase in intraocular pressure.

Prednisolone acetate is not only used for mild to moderate ocular inflammation, but also commonly used for some more serious ocular inflammation, such as uveitis, scleritis, etc., because of its powerful anti-inflammatory effect, it can effectively control the progression of the disease.

Differences in side effects
Although flumilone is relatively mild, long-term or improper use can still increase the risk of eye infections, such as fungal keratitis, etc. Some patients may experience mild increase in intraocular pressure and lens opacity.

When using prednisolone acetate, the risk of eye infection is similar to that of flumilone, but the probability of increased intraocular pressure is relatively higher, and the degree may be more severe. Long-term use is also prone to complications such as posterior subcapsular cataract.

Usage and Dosage
Both are mostly used in the form of eye drops. When using flumilone eye drops, it is usually used 2-4 times a day, 1-2 drops each time, depending on the severity of inflammation; prednisolone acetate eye drops, when the disease is severe, can be used every 1-2 hours, and the dosage is gradually reduced after the disease is relieved. The specific dosage needs to be determined by the doctor according to the actual situation of the patient.

When a doctor has a clinical diagnosis, he should clearly observe the patient's illness, constitution and many other factors, weigh the advantages and disadvantages of flunmyron and prednisolone acetate, and use precise medication to achieve the best curative effect, reduce the disturbance of side effects, and protect the patient's health.