On the Method of Claisen Condensation of Ethyl Acetate
In the past, those who have studied chemistry want to understand the wonderful principle of Claisen Condensation Of Ethyl Acetate. The method starts with ethyl acetate (Ethyl Acetate), supplemented by sodium alcohol and other agents.

In an appropriate vessel, ethyl sodium acetate, put sodium alcohol into it. When the temperature is appropriate, it should not be too strong or too slow. Sodium encounters ethyl acetate, and begins its condensation. The α-hydrogen of the molecule ethyl acetate is captured by sodium alcohol and forms a carbon negative ion. This negative ion is quite active and quickly approaches the carbonyl group of the ethyl acetate molecule. The carbonyl group is active and is attacked by the carbon negative ion, and the bond changes and forms a new one. Oxygen is negatively charged, and protons are obtained later, which then forms an intermediate product.

The intermediate product is not stable, and after intramolecular rearrangement, the ethanol molecule is lost, and the final beta-ketoate is obtained. This beta-ketoate has a wide range of uses in organic synthesis.

The method of ethyl acetate Claisen Condensation is an essential technique in organic synthesis. Scholars need to study its theory carefully and practice it carefully in order to obtain the best effect. In the field of chemistry, explore endless wonders.