On the Method of Cellulose Acetate Phthalate Coating
Looking at modern pharmaceuticals, cellulose acetate phthalate coating is widely used. This coating, so the drug protection, controlled release, extraordinary effect.

If you want to coat cellulose acetate phthalate, you should first prepare all kinds of materials. Cellulose acetate phthalate needs to be pure in quality, accompanied by appropriate solvents, such as alcohols and ketones, to ensure that it is soluble and stable. Plasticizers, such as diethyl phthalate, need to be added to make the coating flexible and not easy to crack.

Its operation is also to use suitable equipment to hold medicine, or as a pot coating machine, or as a fluidized bed. Spray the prepared cellulose phthalate acetate solution evenly on the medicine. When spraying, the speed should be uniform, the amount should be appropriate, and the temperature and humidity should also be carefully adjusted. If the temperature is too high, the solvent will dry quickly, and the coating will be uneven; if it is too low, it will take a long time, and there may be a risk of bonding. The same is true for humidity. If the humidity is too high, the coating will easily absorb moisture and damage its quality.

The coating is ready, when the quality is tested. Looking at its appearance, it should be flat and smooth, without wrinkles and cracks. Measuring its thickness, it must meet the specified standard. More inspection of its dissolution characteristics, in simulated gastrointestinal fluid, cellulose phthalate acetate coating can slowly release the drug at a predetermined time to ensure the effectiveness of the drug.

In short, for cellulose acetate phthalate coating, the selection of materials, the fine operation, and the strict testing are all indispensable. Make good use of this coating method to make excellent pharmaceuticals and benefit patients.