The method of cellulose acetate electrophoresis to detect sickle cells
Taste the essence of medical science, identify diseases, seek their root causes, and take good measures. In the exploration of blood diseases, the method of cellulose acetate electrophoresis to detect sickle cells is very important.

The principle of husband electrophoresis uses the force of an electric field to make charged particles swim. In the blood, various proteins are charged differently. In the cellulose acetate medium, under the action of an electric field, their migration rates are different, so they can be separated.

When detecting sickle cells, take a blood sample from the patient, and after appropriate treatment, obtain a liquid containing hemoglobin. Using cellulose acetate film as a carrier, place it in an electrophoresis tank and pass an electric current. The abnormal hemoglobin of normal hemoglobin and sickle cell has different charges due to structural differences, and the migration distance is also different. After staining and other steps, the distribution of its bands can be clearly seen.

If the bands show abnormal shape and location, combined with clinical manifestations, doctors can determine whether the patient is suffering from diseases related to sickle cells. This detection method is quite accurate, which can provide a solid basis for diagnosis, help doctors to determine treatment, and enable patients to recover. Doctors should study this technique carefully to benefit the common people.