Advantages of cellulose acetate electrophoresis
As an electrophoresis support, cellulose acetate is widely used in the field of biochemical analysis. It has many significant advantages, which are detailed below.

Good resolution
Fine and uniform structure of cellulose acetate, which can effectively separate biological macromolecules of different charged properties and molecular sizes under the action of electric field. Taking serum protein electrophoresis as an example, under specific conditions, it can clearly distinguish albumin, α 1-globulin, α 2-globulin, β-globulin and γ-globulin and other components. Each protein band is well-defined, which is convenient for observation and analysis, and can provide accurate data for clinical diagnosis and biological research.

The electrophoresis speed is fast
The material has weak adsorption force on the sample, reducing the non-specific binding between the sample and the support, so that the sample can migrate smoothly in the electric field. Usually, it only takes tens of minutes to complete a serum protein electrophoresis, which greatly shortens the experimental time and improves the work efficiency compared with traditional supports. It is suitable for scenarios where rapid experimental results need to be obtained, such as clinical emergency testing.

The band is clear
The resulting band edge of cellulose acetate electrophoresis is neat and clear, and the tailing phenomenon is slight. This is due to its good electrical properties and physical structure, which can effectively inhibit the diffusion of the sample, keep the separated zone relatively concentrated, and facilitate the use of optical density scanning and other techniques for quantitative analysis, ensuring the accuracy and reliability of the analysis results.

Easy to operate
The preparation process is not complicated. After the cellulose acetate film is pretreated, the sample is spotted, placed in the electrophoresis tank, and the power supply can be connected for electrophoresis. And no special equipment and complex operation skills are required. The experimenter can be proficient after simple training, and it is suitable for laboratories at different levels to carry out related experiments.

Less sample usage
For precious or scarce biological samples, cellulose acetate electrophoresis has obvious advantages. Only a small amount of samples can be used to complete the separation and analysis. Generally, a few microliters of serum can obtain a clear electrophoresis map, reducing sample waste and providing the possibility for rare sample research.

Good reproducibility
Under the same experimental conditions, cellulose acetate electrophoresis results are stable and have high repeatability. Regardless of different times, different experimental personnel, or in different laboratories, as long as the standard operating procedures are followed, similar electrophoresis results can be obtained, providing a strong guarantee for the comparability and scientificity of experimental data.

In summary, cellulose acetate electrophoresis occupies an important position in many fields such as biochemistry and clinical testing, and has become one of the commonly used techniques for the separation and analysis of biological macromolecules due to its advantages of good resolution, fast speed, clear zone, simple operation, small sample consumption and good repeatability.