The Compendium of Materia Medica contains lead cream, also known as lead white cream, whose chemical composition is lead acetate, which was often used for medicinal purposes in ancient times. Basic lead acetate is also a compound of lead.

The preparation of basic lead acetate is mostly obtained by the reaction of lead and acetic acid. Its properties may be white powder, and under specific conditions, it presents corresponding physical properties. In the past, basic lead acetate was often involved in dyeing, painting and other fields. Because lead is toxic, its use also has potential hazards.

When the ancients understood the concept of basic lead acetate, although it was not as detailed as it is today, some of its characteristics may have been noticed from its practical application. For example, in medicine, although it may be used to treat diseases, its dosage and curative effect should be carefully checked to prevent the harm of lead poisoning. In the application of technology, craftsmen should also be aware of its impact on products in order to make the best use of them and avoid their harm.