What are the applicable populations of prednisolone acetate?

Prednisolone acetate is a commonly used drug, and its applicable population is quite specific.

In patients with hypoadrenal cortex, this drug can supplement the lack of corticosteroids. If the human adrenal cortex is not functioning properly, it cannot secrete hormones normally, causing many physiological functions of the body to be disturbed. Prednisolone acetate can mimic the effect of natural hormones and help the body maintain normal metabolic, immune and other functions, so that patients can slow down symptoms and live as usual.

In people with autoimmune diseases, such as systemic lupus erythematosus and rheumatoid arthritis, the body's immune system mistakenly attacks its own tissues, causing inflammation and damage. This drug can strongly inhibit the immune response, reduce inflammation, relieve joint swelling and pain, erythema and other symptoms, improve the quality of life of patients, and prevent further damage to the organs.

Patients with allergic diseases, such as severe bronchial asthma, drug-induced dermatitis, etc., cause excessive immune reactions due to the body's allergy to specific substances. Prednisolone acetate can quickly suppress allergic reactions, relieve airway spasms, skin itching, redness and swelling, and help patients get out of danger.

In some patients with acute leukemia, prednisolone acetate used in combination with chemotherapy can induce leukemia cell apoptosis and improve the chemotherapy effect. This drug is also used to prevent rejection after organ transplantation, help the transplanted organ survive normally in the patient, and ensure the success of the transplant operation. < Br >
However, it should be noted that this medicine is not suitable for everyone. When using it, be sure to follow the doctor's advice and weigh the pros and cons to ensure the safety and effectiveness of the medication.

What are the side effects of prednisolone acetate?

Prednisolone acetate (Prednisolone Acetate) is a glucocorticoid drug. Although it has significant efficacy, it also has many side effects. The ancients said: "It is a three-point poison of medicine", and this drug is no exception.

First, it has a quite significant impact on metabolism. Long-term use can easily cause water and sodium retention, as if the water storage pool in the body is out of control, and the water is flooded, which can cause edema, unprovoked weight gain, and bloated body. And sugar metabolism is disordered, blood sugar rises, as if the sugar regulation mechanism in the body is in chaos, like a runaway horse, which is easy to induce steroid diabetes. Fat metabolism is also disturbed, and fat distribution is abnormal, resulting in cardiac obesity, showing a "full moon face" and a "buffalo back" state. The face and body shape are different from ordinary people.

Second, it has a great impact on skeletal muscles. It can inhibit the activity of osteoblasts, just like the craftsmen of construction who are slow to work, the formation of bones is reduced, the bone is gradually thinning, and it is easy to cause osteoporosis. The bones are fragile like rotten wood, and if you don't pay attention, you may fracture. Muscles are also implicated, and there is myasthenia. The limbs seem to lose their vitality in the past, and they are slow to move and unable to move.

Third, the immune system is suppressed. Although this drug can calm the "fire" of immunity in the body, it also makes the immune defense line like a fragile barrier. The body's ability to resist external evil is greatly reduced, just like the door is wide open, bacteria, viruses and other foreign enemies can easily invade, so the risk of infection is greatly increased, colds, colds and other diseases are frequent, and the disease is often serious after infection, and it is difficult to heal.

Fourth, it also irritates the gastrointestinal tract. It is easy to cause damage to the gastrointestinal mucosa, like a sharp blade to cut through the delicate mucosa, causing stomach pain, stomach swelling, nausea, vomiting and other discomfort, and even cause ulcers and bleeding, like a hidden crisis in the gastrointestinal tract, threatening the health of the body at all times.

Fifth, the mental aspect is also affected. After taking the medicine, some patients seem to have changed their temperament, develop mental symptoms, or be excited and restless, or be depressed and anxious, and their emotions are fluctuating like waves, which seriously affects their life and physical and mental health.

To sum up, when using prednisolone acetate, it is like walking on thin ice, weighing the pros and cons, being cautious, and not blindly abusing it.

What is the usage and dosage of Prednisolone Acetate?

Prednisolone acetate (Prednisolone Acetate) is a commonly used glucocorticoid drug with anti-inflammatory, anti-allergic, immunosuppressive and other effects. Its usage and dosage vary depending on the disease, condition and individual patient differences, as detailed below:
- ** Oral administration **:
- ** General disease **: The initial dose is usually 10-60mg per day, depending on the severity of the disease. For autoimmune diseases, the initial dose may be larger, and then gradually reduced as the disease eases. Generally speaking, the dose can be reduced by 5mg per week or every two weeks according to the condition to the maintenance dose. The maintenance dose is mostly 5-10mg per day, which aims to consolidate the curative effect and prevent the recurrence of the disease.
- ** Special diseases **: Take systemic lupus erythematosus as an example, during the active period of the disease, the initial dose may reach 40-60mg per day. After the disease is controlled and the symptoms improve, slowly reduce the dose. For some allergic diseases, those with mild symptoms, the initial dose may be 10-20mg per day. After the symptoms are controlled, the dose should also be gradually reduced and stopped.
- ** Injection administration **:
- ** Intramuscular injection **: The usual dose is 10-40mg per day. If it is used for acute severe allergic reactions and cannot be administered orally, an appropriate amount of prednisolone acetate can be injected intramuscularly to quickly control symptoms.
- ** Intraarticular injection **: The dose depends on the size of the joint. For small joints such as fingers and toe joints, the injection dose is about 2.5-5mg; for large joints such as knee and hip joints, the dose may reach 10-40mg. This injection method is often used to treat arthritis and can directly act on diseased joints to reduce inflammation and pain. However, intra-articular injection should not be too frequent to avoid adverse reactions such as joint cartilage damage. It is usually injected once every 1-3 months.

It should be noted that the usage and dosage of prednisolone acetate must be accurately formulated by a professional doctor according to the specific condition of the patient. Patients should not increase or decrease the dose or stop the drug at will, so as not to affect the treatment effect or even cause serious adverse reactions. During the medication period, patients should be regularly reviewed to facilitate physicians to adjust the treatment plan in a timely manner according to changes in their condition.

Does Prednisolone Acetate interact with other medications?

An Shi Glucose skin hormones can increase coagulation factors, the anticoagulation effect may be weakened, and the disease of thrombosis cannot be ignored.

Then and hypoglycemic, the two meet, and it is embarrassing. Nisone acetate can raise blood sugar, and the effect of hypoglycemic may be offset. Blood sugar waves are controlled, and patients can be treated with double-ocinia.

And it is used for the purpose of the environment. Due to hormone-induced dysfunction, the sensitivity of the myocardium is increased, and the risk of arrhythmia is in the shape.

Another liver enzyme, such as phenobarbital, can accelerate the replacement of nisone acetate, and the effect is reduced. The inhibition of liver enzymes, such as ketoconazole, can cause hormone substitution, increase blood pressure, and increase adverse reactions.

Therefore, the use of the drug, such as walking on the road of thorns, if you don't pay attention, the patient will grow. For bed use, it is necessary to check the interaction of the drug, and balance the advantages and disadvantages to ensure the well-being of the patient.

What should be paid attention to when using prednisolone acetate?

Alas! Prednisolone acetate is a medicine commonly used by doctors. When it is used, all kinds of matters must not be ignored.

Bearing the brunt of it, you must follow the doctor's advice. Doctors, with their professional knowledge, measure the patient's condition and body shape, and determine the amount and time of medication. If the patient increases or decreases without authorization, or the effect of the medicine is not reached, the disease cannot be cured, or even all kinds of syndromes occur. For example, Song Dou Cai's "The Letter to the Heart of Qian Que" says: "The way of medicine is subtle to the minute, and the medicine is like using a soldier. The difference is the slightest, and it is a thousand miles." The amount of medication is related to success or failure, but it can be careless!

Furthermore, know its taboos. If you are allergic to this product, you must not use it. Otherwise, allergies, such as itching and rash on the skin in mild cases, and shortness of breath and convulsion in severe cases, are at stake. And pregnant women and breastfeeding women need to be especially cautious when using medication. Cover the fetus and baby, if the body is not fully charged, the medicine is biased, and it is easy to hurt it. In the past, "Qianjin Yaofang" said: "When a woman is pregnant, the medication must be clear about its nature, and avoid its severity to prevent fetal injury." This can be seen here.

In addition, those who use this medicine for a long time should pay attention to its adverse reactions. Such as osteoporosis, blood sugar rise, and high blood pressure can all be present. Therefore, during the medication period, it is necessary to regularly check bone mineral density, blood sugar, blood pressure, etc. Just as the ancients said: "Prediction is established, and if you don't predict it, you will be useless." Early detection and early prevention can avoid serious diseases.

And sudden withdrawal of medicine is also not advisable. When the dose is gradually reduced to prevent the disease from rebounding, or the disease of adrenal cortex dysfunction. This is like walking on a boat in water, and the boat is easy to overturn if you stop suddenly. In "Treatise on Typhoid", when it comes to the method of medication, it is also important to slow down the picture, so as not to make the disease recover.

In short, the use of prednisolone acetate must be carried out with caution, follow the doctor's instructions, understand its taboos, observe its reaction, and slow down the medicine. Only then can you obtain the benefits of the medicine and avoid its harm.