Uranyl Acetate

Specifications

HS Code	396412
Chemical Formula	UO2(C2H3O2)2
Molar Mass	424.15 g/mol
Appearance	Yellow - green crystalline solid
Solubility In Water	Soluble
Melting Point	280 °C (decomposes)
Density	2.89 g/cm³
Odor	Odorless
State At Room Temperature	Solid
Hazard Class	Radioactive, Toxic
Uses	Stain in electron microscopy, uranium source in some chemical processes

As an accredited Uranyl Acetate factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage

Packing	100 - gram vial of Uranyl Acetate packaged securely for safe handling.
Storage	Uranyl acetate is a toxic and radioactive chemical. Store it in a cool, dry, well - ventilated area away from heat sources and incompatible substances like reducing agents. Keep it in a tightly - sealed container, preferably in a dedicated radioactive material storage cabinet. Follow strict regulatory procedures for handling and storage to prevent environmental release and exposure risks.
Shipping	Uranyl acetate, a radioactive chemical, is shipped in specialized, leak - proof containers. These are designed to meet strict safety regulations, ensuring secure transportation and minimizing radiation exposure risks during transit.

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General Information

Historical Development

Uranyl Acetate is a chemical object. At the beginning, the method of preparation was still simple and rough, and the quality of the product was not yet perfect. However, with the passage of time, the ambition of scholars has become stronger and deeper. After repeated efforts, the preparation method has become more and more refined, and its quality has gradually improved. From the ignorance of the past to the complete maturity of the preparation process today, Uranyl Acetate has been widely used in chemistry and occupies an important place in the field of scientific research, which is a significant trace in the development of chemistry.

Product Overview

Uranyl Acetate is an organic uranium compound with the chemical formula (UO₂)(CH₃COO)₂・xH₂O. It is usually a yellow crystal or powder containing 2-3 water of crystallization. It is easily soluble in water and alcohol. The solution is yellow-green. It is both radioactive (α radiation) and toxic. It is mainly used as a negative stain for biological samples in electron microscopy. It can also be used for the analysis, purification and preparation of related compounds of uranium. It must be stored and handled in accordance with the regulations for radioactive and toxic substances.

Physical & Chemical Properties

Uranyl Acetate is a chemical research object. Its physical and chemical properties are particularly important. Looking at its color, it is often light yellow, and if it is crystalline, it is quite crystal clear. In terms of its physical rationality, the melting point and boiling point have specific numbers, which are related to the change of its state. And in terms of solubility, it is soluble in a certain type of solvent, which is of great significance in experimental operation and application.
As for its chemistry, it has a certain reactivity. It can react with various reagents to form different compounds. The atomic bonding method in its structure determines its chemical behavior. In the investigation of the chemical reaction mechanism, the chemical properties of Uranyl Acetate are the key factors that affect the process and products of the reaction. They play a significant and indispensable role in the field of chemical research.

Technical Specifications & Labeling

Nowadays, there is uranyl acetate, and its process specifications and identification (product parameters) are the key. The process specifications are related to the preparation method, from the selection of raw materials, the accurate ratio, to the reaction conditions, temperature and pressure. High-purity raw materials must be used to control the temperature in a suitable range according to the precise ratio, so that the reaction is sufficient and stable.
In terms of identification (product parameters), such as purity needs to reach a very high standard, and the impurity content is minimal. Its crystal morphology and color are also identification elements. When it shows a specific shape and color, it is considered to be distinguishable. The size and uniform distribution of particles also affect its performance. Only with accurate process specifications and clear and accurate identification can this uranyl acetate be suitable for use in scientific research and industry.

Preparation Method

Uranyl acetate is usually prepared by reacting uranium oxide (such as uranium trioxide, uranium trioxide) or uranium salt (such as uranyl nitrate) with acetic acid or acetic anhydride. The specific steps are: dissolve uranium oxide in dilute acetic acid solution, react under heating conditions to generate uranyl acetate solution, evaporate and concentrate, cool and crystallize to obtain a product containing crystal water; or react uranyl nitrate with acetic anhydride to generate uranyl acetate by replacing nitrate ions. The temperature and pH value need to be controlled during the reaction, and finally the crystals are obtained by purification and drying. The whole process needs to be carried out under ventilation conditions to strictly prevent radioactive and toxic hazards.

Chemical Reactions & Modifications

The chemical reaction of uranyl acetate is mainly reflected in the coordination and substitution reaction of uranyl ions (UO₂²⁺), such as forming multinuclear complexes with nitrogen- and oxygen-containing ligands (such as ethylenediamine, carboxylic acids, etc.), or reacting with carbonates and phosphates to generate corresponding uranyl precipitates; under acidic conditions, it can be reduced to low-valent uranium compounds by strong reducing agents (such as zinc powder, ascorbic acid). Its modification is usually achieved by introducing organic ligands (such as amino acids and multidentate carboxylic acids) to regulate the coordination environment, or by preparing uranyl functional materials in combination with polymer materials to change its solubility, stability and optical/catalytic properties. The modification process needs to be combined with radioactive protection requirements and carried out in an inert atmosphere or sealed system to avoid uranyl ion leakage and radiation risks.

Synonyms & Product Names

Uranyl acetate
Uranyl diacetate
Uranium acetate
Acetic acid, uranyl salt
Uranyl ethanoate
Uranyl acetate dihydrate
Uranium(2+) diacetate dihydrate
CAS: 541-09-3
IUPAC: diacetatodioxouranium

Safety & Operational Standards

Uranyl Acetate is a radioactive and toxic chemical substance. When using it, relevant management regulations must be strictly followed. Experimental operations should be carried out in a fume hood or a closed glove box. The operator must wear radiation-proof work clothes, impermeable gloves and efficient respiratory protection to avoid direct skin contact, inhalation of particles or accidental ingestion. The chemical should be sealed and stored in lead cans or thick plastic containers in a cool, light-proof special radioactive material warehouse. The warehouse should be double-locked and away from food and reducing agents. Waste should be classified and managed, and handled by professional units as radioactive and toxic waste. It is usually disposed of by solidification and deep burial. A license for the use of radioactive materials must be obtained before use, and the operator must receive radiation protection and emergency response training. In the event of a leak, the contaminants should be immediately covered and collected with inert materials, and the radioactive emergency plan should be activated at the same time to control the spread of uranyl ions and prevent personnel exposure.

Application Area

Uranyl Acetate is a chemical product. Its application fields are quite extensive. In biological microscopy, it is often used as a staining agent. It can make the fine structure of organisms clearly visible under electron microscopy, helping researchers to understand the mysteries of cells, and the delicate structure of organelles.
In the field of materials science, it can be used to modify the surface of materials and endow them with specific properties. Such as changing the hydrophobicity of materials, affecting their interaction with surrounding substances. Make materials exhibit unique properties under specific environments, or enhance their stability, or enhance their reactivity.
Furthermore, in some chemical analysis methods, it is also an important reagent. It can use its chemical reaction with specific substances to achieve accurate detection and quantitative analysis of target components, providing key data support for scientific research and industrial production.

Research & Development

Uranyl acetate research and development efforts largely focus on its numerous applications as well as finding safe alternatives. Electron microscopy uses this substance as a negative stain, binding with components like nucleic acids to increase contrast and image clarity for ultrastructures, aiding researchers in studying microscopic structure of living organisms closely. Due to its radioactivity and toxicity, most countries around the world strictly regulate its use and circulation. Uranyl acetate solution can be used in analytical chemistry for titration or color development depending on concentration levels; additionally it's perfect for detecting specific components that require analysis.

Toxicity Research

The toxicity of Uranyl Acetate is a matter of urgency. Its substances are often used in experiments, but the toxicity is unknown, and it is a hidden danger.
Examine all kinds of experiments in the past, using white pigs, guinea pigs, etc. as tests. When fed with this agent, it didn't take long for the white pigs to slow down, eat less, and lose their hair; guinea pigs have convulsions from time to time. Looking at it, there are many abnormal changes in the organs, the liver is dark and soft, and the kidneys are also showing signs of damage.
And look at its effect on cells. In a petri dish, after the cells are exposed to this agent, the proliferation is blocked, the morphology is also changed, and some of them are actually apoptotic. It can be seen that Uranyl Acetate has significant toxicity and can harm the physiological function of organisms. In the future, we should study its toxicological mechanism in depth, and pay attention to its potential harm to the environment and the human body, so as to prevent problems before they occur, so as to avoid disasters.

Future Prospects

Uranyl acetate has broad research prospects, but it also faces challenges. In the field of biomedical imaging, uranyl acetate, as a commonly used stain for electron microscopy, can enhance the contrast of cell structure imaging and help explore the microscopic mechanisms of life. Especially in the correlated light electron microscopy (CLEM) technology, it can induce fluorescence at low temperatures and achieve precise correlation between fluorescence and transmission electron microscope images. It is expected to play a greater role in the study of cell processes. However, due to its radioactivity and toxicity, international regulations have become increasingly stringent, and its access and use are restricted. Finding safe and effective alternatives has become a research hotspot. In the future, on the one hand, it is necessary to deeply explore the new properties of uranyl acetate to expand its applications, and on the other hand, it is necessary to accelerate the research and development of non-toxic or low-toxic alternatives to promote sustainable development in related fields.

Where to Buy Uranyl Acetate in China?

As a trusted Uranyl Acetate manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.

Frequently Asked Questions

As a leading Uranyl Acetate supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What is Uranyl Acetate?

Uranyl acetate is an important salt compound in chemistry. It is formed by the combination of uranyl ions (UO ² ²) and acetate ions (CH ² COO). This compound is often in the form of yellow crystals and can exist stably under specific conditions. It has important uses in many fields, one of which is electron microscopy. Because it can combine with biological macromolecules and produce different scattering effects under electron beams, it can clearly show the fine structure of biological samples under electron microscopy, helping researchers to deeply explore the mysteries of the microscopic world of biology. Furthermore, uranyl acetate also has its unique role in nuclear chemistry-related research. Uranium plays a key role in the field of nuclear energy. As a form of uranium, this compound provides assistance in studying the chemical properties and reaction mechanism of uranium, and lays a theoretical foundation for the safe and efficient use of nuclear energy. However, due to its radioactive content, it is necessary to follow strict safety regulations during use and storage to prevent harm to the human body and the environment. Proper protection and management can ensure that it plays a positive role in scientific research and other application scenarios, and avoid its harm.

What fields is uranyl acetate mainly used in?

Uranyl acetate , which is important in a wide range of domains. In the study of biological matter, it is often used as a dyeing agent for microparticles. Biological matter is usually low in density, and a sufficient ratio is formed at the bottom of the body. Uranyl acetate can interact with biological macromolecules such as proteins and nucleic acids to increase their density, so that the ultrafine particles of cells, such as cell membranes and organelles, can be clearly displayed in the image, helping researchers to explore the mysteries of biological matter. The production process of some functional materials, uranyl acetate can be used as a raw material or catalyst. For example, in the synthesis of some materials with special optical and chemical properties, it can reflect the crystalline phase and morphology of the material, and control the properties of the material, so that the material is more suitable for specific application needs, such as the research of new semi-metallic materials. Furthermore, in chemical analysis, uranyl acetic acid can be used for quantitative analysis of specific elements or compounds. Using the characteristics of some substances to reduce the reaction, through the reflection of the reaction or the determination of the phase, the composition and content of the substance can be determined, and the role can be determined in environmental analysis, chemical analysis, etc., to help analysts clarify the formation of the substance.

What are the precautions for the use of uranyl acetate?

Uranyl acetate is a commonly used product. It should be used with caution. This product is radioactive and harmful. Therefore, when operating, it is necessary to use protective equipment, such as clothing, gloves, eyes, etc., to prevent the body from being shot. And the operation is suitable for the place where it is used. This product needs to have perfect prevention and protection to ensure environmental safety. Furthermore, when using it, it should be fine and careful. Because of its special nature, the amount is large, and the impact is very large. If the amount is small or the effect is obtained in the long term, if the amount is large, it will be unexpected. Therefore, if the measuring device is taken, it must be refined, and it should be used in the original position, and it should be properly stored to avoid poor pools. Its dissolution in the liquid, pay attention to the dissolution and degree of dissolution, etc. Different dissolution, different degrees of dissolution, or cause its solubility and chemistability to be low. If it is dissolved, it may need to be mixed and dissolved, and then it is appropriate to avoid the solution from being released. When it is used up, the things left behind must not be left behind. Because of its radioactivity, it should be taken care of according to the phase. Or send it, or make special arrangements, in order to avoid the danger of radiation pollution and protect the well-being of people in the environment.

What are the physical and chemical properties of uranyl acetate?

Uranyl acetate is a yellow crystal at room temperature, with luster, in the form of columnar or needle-like crystals. Melting point is about 119 ° C, heated to 275 ° C decomposition. Easily soluble in water, in 100 grams of water, about 28 grams at 25 ° C, higher solubility in hot water. Also soluble in organic solvents such as ethanol and acetone. From a chemical point of view, its aqueous solution is weakly acidic, due to the hydrolysis of uranyl ions. Uranium dioxide acetate is oxidizing, and in the case of reducing agents such as ascorbic acid, the valence of uranium elements can be reduced. It can form complexes with certain organic reagents, such as 8-hydroxyquinoline, and this property is often used in the determination and separation of uranium in analytical chemistry. When reacting with bases, uranium hydroxide precipitates are formed. Uranium dioxy acetate is not stable under light, and its structure changes due to photolysis. In the field of radiochemistry, due to uranium-containing elements, it is radioactive. Although it is relatively weak compared to some other compounds of uranium, it still needs protection during operation to avoid radiation hazards.

How to properly store uranyl acetate?

The storage of uranyl acetate must follow strict regulations: double-sealed lead or high-density polyethylene containers should be used, and it should be stored in a dedicated radioactive material warehouse with independent ventilation, maintained at a room temperature of 10-30°C, and avoided from light and moisture; it is strictly forbidden to store it together with reducing agents, acids, food and medicines, etc. The storage cabinet must be managed by two people with two locks, and radioactive warning signs and MSDS (Material Safety Data Sheet) must be posted in a prominent position to ensure storage safety and prevent leakage and accidental contact risks.