Chlorhexidine Acetate
Triacetin Series Acetate Series Basic Chemicals Casting Materials Organic Ester Series Composite Carbon Source Liquid

Chlorhexidine Acetate

    Specifications

    HS Code

    646077

    Chemical Formula C22H30Cl2N10·2C2H4O2
    Molecular Weight 625.58 g/mol
    Appearance White or almost white powder
    Odor Almost odorless
    Solubility Soluble in water, slightly soluble in ethanol
    Ph 4.0 - 6.0 (1% solution)
    Melting Point 155 - 160 °C
    Antibacterial Activity Broad - spectrum antibacterial, effective against Gram - positive and Gram - negative bacteria
    Stability Stable under normal conditions
    Mode Of Action Disrupts cell membranes and cytoplasmic content leakage

    As an accredited Chlorhexidine Acetate factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing 100 - gram bottle of Chlorhexidine Acetate, securely packaged for chemical use.
    Storage Chlorhexidine acetate should be stored in a cool, dry place, away from direct sunlight. Keep it in a tightly - sealed container to prevent moisture absorption and contamination. Store at room temperature, typically between 15 - 30°C. Avoid storing near heat sources or flammable materials. Proper storage ensures its stability and effectiveness over time.
    Shipping Chlorhexidine acetate, a regulated chemical, is shipped in well - sealed containers. Special care is taken to ensure compliance with safety regulations, preventing leakage during transit to maintain environmental and handling safety.
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    Chlorhexidine Acetate Chlorhexidine Acetate Chlorhexidine Acetate
    General Information
    Historical Development
    Chlorhexidine acetate, its origin originated in modern chemical research. At the beginning, many wise men explored the field of chemistry in depth, hoping to find a strong bactericidal clean. After a long time of research, chlorhexidine acetate gradually appeared in the world.
    It was first used in medicine, because of its bactericidal power, it is quite effective in preventing staining of wounds and detoxifying medical equipment. With the passage of time, its use is also widespread, involving oral care and daily cleaning. In the past, the concept of hygiene was not as prosperous as it is today, but chlorhexidine acetate was developed to help control bacteria and protect health. From medicine and the people, it has gradually become a commonly used product in the world, contributing to all things health, witnessing the progress of hygiene concepts and chemical techniques, leaving traces in the evolution of history.
    Product Overview
    Chlorhexidine acetate is a commonly used disinfection and sterilization chemical. It is stable and easily soluble in alcohol and water. In the medical field, it is often used as a disinfectant, which can be used for disinfection of skin and mucous membranes, and also for hand disinfection of healthcare workers before surgery. It can effectively kill many germs, such as Gram-positive bacteria, negative bacteria and fungi.
    Looking at the characteristics of this substance, it has high efficiency and long-lasting antibacterial power, and is less irritating to skin mucous membranes, so it is widely used. In the pharmaceutical industry, it is often added to various external preparations, such as lotions, creams, etc., to ensure product hygiene. In daily life, some disinfection products also contain chlorhexidine acetate, which can be used for environmental surface disinfection and build a protective net for people's health.
    Physical & Chemical Properties
    "On the Physical Properties of Chlorhexidine Acetate"
    Chlorhexidine acetate is also a chemical product. Its properties are stable, and the norm is white or almost white crystalline powder. Slightly soluble in water, but slightly soluble in ethanol. It has antibacterial properties and has the effect of suppressing both Gram-positive and negative bacteria. Its antibacterial mechanism is adsorbed on the permeable barrier of bacterial cytoplasmic membranes, causing cell contents to leak out and cause bacterial death. In the field of medicine, it is often used as a disinfectant and can be used for skin and mucosal disinfection, hand washing before surgery, etc. Its unique physical and chemical properties, good stability and strong antibacterial activity are the foundation for its wide application in medical and health care and many other aspects. It is actually an important category of chemical products.
    Technical Specifications & Labeling
    Chlorhexidine Acetate is a good medicine for disinfection and anti-corrosion. Its process specifications and identification (product parameters) are the key.
    On its process specifications, it must be made with high-purity raw materials according to precise proportions and rigorous processes. From the screening of raw materials, it is necessary to be pure and free of impurities, and those with impurities cannot enter. To the reaction process, the control of temperature, humidity and time cannot be ignored. If there is a slight difference, the quality will change.
    As for the logo (product parameters), on the packaging, the product name, content, production date, shelf life, etc., must be clearly identifiable. The standard of content, when accurate, is related to the efficacy of the drug. The production date and shelf life indicate the time limit. If it expires, the efficacy of the medicine may be reduced or even harmful.
    In this way, strictly abide by the process specifications and clearly identify (product parameters), in order to obtain high-quality products of Chlorhexidine Acetate to meet the needs of medicine and health.
    Preparation Method
    The preparation of Chlorhexidine Acetate is the key to the raw materials and production process. Take an appropriate amount of dichlorobenzohexane and mix it with acetic acid in a specific ratio. First put dichlorobenzohexane in a clean vessel, slowly inject acetic acid, and continue to stir during the process to fully integrate the two. The reaction conditions need to be precisely controlled, and the temperature should be maintained in a moderate range. If it is too high, the product will be easy to decompose, and if it is too low, the reaction will be slow. When the reaction is complete, after a series of subsequent treatments, such as filtration to remove impurities, evaporation and concentration to enrich the product, and then crystallize and precipitate, Chlorhexidine Acetate is obtained. The recycling mechanism of its production process lies in the recycling of unreacted raw materials to improve the utilization rate of raw materials, and the reaction steps are rigorous and orderly, each step is related to the quality of the product. This preparation method can ensure the production of high-quality Chlorhexidine Acetate products.
    Chemical Reactions & Modifications
    Chlorhexidine acetate is a commonly used chemical for disinfection and antibacterial. Its chemical reaction is related to the performance of the preparation. In the past, the method of its synthesis was studied, and after many tests, a pure product was obtained. However, the harsh reaction conditions, such as temperature, pH, etc., all have an impact. If you don't pay attention, the product is impure and the efficiency is discounted.
    After that, the researchers thought about changes and improved the reaction path. On top of the selection of solvents and the addition of catalysts, painstaking efforts were made. After the change, the purity of the product was greatly increased and the stability was also excellent. Looking at the change in its chemical properties, from the initial flaws to the current excellence, it is the work of unremitting research and change. In this way, chlorhexidine acetate is used in the field of disinfection and sterilization in a better state to protect the health of the public.
    Synonyms & Product Names
    Chlorhexidine acetate
    Chlorhexidine diacetate
    1,1'-Hexamethylenebis[5-(p-chlorophenyl)biguanide] diacetate
    Acetic acid, compound with 1,1'-hexamethylenebis[5-(p-chlorophenyl)biguanide] (2:1)
    Chlorhexidine monoacetate
    Chlorhexidine ethanoate
    CAS: 56-95-1
    IUPAC: 1,1'-hexamethylenebis[5-(4-chlorophenyl)biguanide] diacetate
    Safety & Operational Standards
    "Code of Safety and Operation of Chlorhexidine Acetate Products"
    Chlorhexidine acetate is a commonly used disinfection and antibacterial agent, which is widely used in medical and health care, daily chemical and other fields. To ensure its safe use and orderly operation compliance, the following specifications should be followed.
    First of all, the importance of storage. Chlorhexidine acetate should be placed in a cool, dry and well-ventilated place. Cover the heat and light of sunlight, or cause its chemical properties to deteriorate and damage its efficacy. And it needs to be kept away from fire and heat sources, because although it is not flammable and explosive, it is not suitable for temperature environment, or it affects its quality.
    As for the operation process, make sure that the operator cleans his hands first, wears clean work clothes, and wears gloves and masks if necessary. When using, when using clean utensils, take them according to the exact method, and do not increase or decrease at will. When dispensing the liquid, it is necessary to dissolve it in an appropriate solvent in strict accordance with the specified ratio, stir evenly to ensure accurate concentration.
    When using it for disinfection, the object and scene of use should be carefully observed. Disinfect the skin, dilute it to an appropriate concentration, and apply or wipe it evenly. For disinfection of medical apparatus, make sure that the instrument is fully immersed in the prepared liquid for a specified time. After use, properly dispose of the remaining liquid, and do not pour it at will to prevent pollution of the environment.
    Furthermore, if you accidentally touch the skin or eyes during use, rinse with plenty of water as soon as possible. If you feel unwell, seek medical attention urgently.
    Strictly abide by the safety and operating standards of chlorhexidine acetate to obtain its benefits and avoid its harm, and ensure the safety of all parties.
    Application Area
    Chlorhexidine Acetate is widely used in the medical, daily chemical and industrial fields. In the medical field, it has strong broad-spectrum antibacterial properties and is often used for preoperative skin disinfection, wound washing, oral rinses (such as gingivitis treatment) and medical device immersion disinfection; in the daily chemical industry, it is added to hand sanitizers, shower gels, skin care products and deodorants to play an antibacterial and cleaning role; in the industrial field, it can be used as a preservative in paints, glues and other products to prevent microbial contamination. At the same time, it can also be used for livestock and poultry house disinfection and equipment cleaning in animal husbandry. With its stable antibacterial properties, it can effectively control microorganisms in multiple scenarios.
    Research & Development
    The research and development of chlorhexidine acetate is centered around its antibacterial properties. The bactericidal mechanism of destroying microbial cell membranes and protein denaturation has been clarified, and it can maintain antibacterial activity in the skin and mucous membranes for a long time. Currently, we are committed to the research and development of innovative dosage forms, such as gels and films, to improve efficacy and compliance. In addition to traditional medical disinfection, daily chemicals and industrial preservation, we are also exploring new uses such as livestock disinfection and fruit and vegetable preservation. At the same time, in order to address the problem of microbial resistance, we are conducting research on combined use with other antibacterial ingredients to optimize antibacterial performance and expand the scope of application.
    Toxicity Research
    The toxicity of chlorhexidine acetate is dose- and exposure route-dependent: when used topically, low concentrations are generally safer, but may cause skin and mucous membrane irritation, such as burning, itching, or allergic reactions, and eye contact may lead to corneal damage; oral ingestion toxicity is relatively low, but high doses may still cause gastrointestinal reactions such as nausea, vomiting, and abdominal pain, and even affect the central nervous system; long-term and large-scale use poses potential risks, including oral flora imbalance, tooth staining, and ecotoxicity to aquatic organisms; its toxicity mechanism is related to the destruction of the cell membrane lipid bilayer and interference with cell metabolism. Current research is focusing on the chronic toxic effects of long-term exposure and safety assessments of special populations (such as pregnant women and children) in order to develop more scientific usage specifications.
    Future Prospects
    Looking at today's world, technology is changing day by day, and all kinds of things are showing extraordinary potential. Chlorhexidine Acetate also contains infinite prospects. In the field of disinfection and sterilization, its effect is outstanding, it can control many germs and ensure everyone's health.
    Looking to the future, Chlorhexidine Acetate will be more effective in many aspects such as medical health and daily use. In medical treatment, or to help wounds heal quickly, prevent infections, and become a medical assistant; in daily use, it can add all kinds of clean things to protect the daily hygiene of the public.
    Although the road ahead may encounter challenges, the progress of science and technology and the depth of research will surely be able to overcome it. Our scientific researchers should dedicate their efforts to exploring its potential, so that Chlorhexidine Acetate will shine in the future, for the well-being of the world, and make great achievements.
    Where to Buy Chlorhexidine Acetate in China?
    As a trusted Chlorhexidine Acetate manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
    Frequently Asked Questions

    As a leading Chlorhexidine Acetate supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What is the scope of application of chlorhexidine acetate?
    Chlorhexidine acetate is suitable for antibacterial and disinfection scenarios in many fields: in medicine, it can be used for pre-operative skin disinfection, wound washing, oral gargle (such as gingivitis treatment) and medical device soaking; in the daily chemical industry, it is added to hand sanitizers, shower gels, skin care products, etc. to play an antibacterial and cleaning role; in the industrial field, it is used as a preservative in coatings, glues, etc. to prevent microbial contamination; in animal husbandry, it can be used to disinfect livestock and poultry houses and utensils; in addition, it can also be explored for use in scenarios such as fruit and vegetable preservation. With its broad-spectrum antibacterial properties, it has application value in environments where microbial reproduction needs to be controlled.
    What are the side effects of chlorhexidine acetate?
    The side effects of chlorhexidine acetate mainly manifest as local irritation and allergic reactions, such as burning sensation, itching, erythema or rash after contact with the skin and mucous membranes, and corneal damage after eye contact; long-term oral use can easily cause tooth staining, taste changes and oral flora imbalance; high-concentration oral administration may cause gastrointestinal discomfort such as nausea, vomiting, abdominal pain, and even central nervous system depression; in addition, long-term and large-scale use may also cause ecotoxicity to aquatic organisms, and there is a potential risk of microbial resistance. Safety should be carefully evaluated when used by special populations (such as pregnant women and children).
    How to Use Chlorhexidine Acetate Correctly?
    The correct use of chlorhexidine acetate requires the selection of appropriate dosage forms and concentrations according to different scenarios: in medical disinfection, 0.5% - 2% solution (often in combination with ethanol) is commonly used for surgical skin disinfection, 0.05% - 0.1% solution is used for wound washing, and 0.02% - 0.1% solution is used for oral gargle and long-term use should be avoided to prevent tooth staining; formula standards must be followed in daily chemical products, and the concentration of topical preparations such as hand sanitizers is usually less than 0.3%; 0.1% - 0.5% solution should be used for instrument immersion disinfection and attention should be paid to the action time; avoid contact with sensitive areas such as eyes during use. If accidental contact occurs, rinse immediately with clean water; special populations (such as pregnant women and children) should use it under the guidance of a doctor, and be alert to allergic reactions. If any discomfort is found, stop using it and seek medical attention in time. At the same time, avoid using it in combination with soap, anionic surfactants, etc. to prevent reduced efficacy.
    Does chlorhexidine acetate interact with other drugs?
    Chlorhexidine acetate may interact with a variety of drugs. Because it is a cationic surfactant, its efficacy will be reduced due to charge neutralization when used with soap or anionic surfactants (such as sodium dodecyl sulfate). Redox reactions may occur when used with strong oxidants such as iodine preparations and potassium permanganate, weakening the antibacterial activity. When used in combination with certain cationic drugs (such as benzalkonium bromide), it may compete for the action sites and affect the antibacterial effect. When used in combination with sulfonamides and alkaloids, precipitation or adsorption may occur, reducing drug solubility and bioavailability. In addition, when mixed with alcohol-containing preparations, it may increase skin and mucous membrane irritation. When using it, it is necessary to avoid random compatibility with the above-mentioned drugs. If combination use is necessary, professional medical staff should be consulted to ensure medication safety and efficacy.
    What is the preservation method of chlorhexidine acetate?
    The storage of chlorhexidine acetate should follow the principles of avoiding light, sealing, and keeping it in a cool and dry place. It should usually be stored at room temperature (10-30℃) and avoid direct sunlight and high temperature and humidity to prevent drug degradation or deterioration; its aqueous solution or preparation should be sealed and stored in the original container to prevent volatilization or contamination, and special attention should be paid to avoid contact with metal containers to avoid chemical reactions that affect stability; alcohol-containing compound preparations should be kept away from fire sources to prevent the risk of combustion and explosion; different dosage forms (such as solutions, suppositories, ointments, etc.) should be stored according to the storage conditions marked on the instructions. It is prohibited to use them when they are expired or have changes in properties (such as discoloration, turbidity, precipitation) to ensure the quality and safety of the drug.